Those who submit to Christ's lordship have an increase of strength and knowledge of Him. They literally gain a new mental and physical strength. They do not faint along the way because Jesus pours His own strength into them as they go.
"For this cause we also, since the day we heard it, do not cease to pray for you, and to desire that ye might be filled with the knowledge of his will in all wisdom and spiritual understanding; that ye might walk worthy of the Lord unto all pleasing, being fruitful in every good work, and increasing in the knowledge of God; strengthened with all might, according to his glorious power, unto all patience and longsuffering with joyfulness" (Colossians 1:9-11).
God will keep those who submit to His lordship blameless to the day of Christ's coming. If we submit to Jesus—doing as He commands, not leaning on our own understanding—we will never lack anything. He will supply everything we need to please Him. The Lord Himself will hold and keep us blameless to the very end!
"That in every thing ye are enriched by him, in all utterance, and in all knowledge; even as the testimony of Christ was confirmed in you: so that ye come behind in no gift; waiting for the coming of our Lord Jesus Christ: who shall also confirm you unto the end, that ye may be blameless in the day of our Lord Jesus Christ. God is faithful, by whom ye were called unto the fellowship of his Son Jesus Christ our Lord" (1Corinthians 1:5-9).
We are to entrust our lives into Jesus' care. It then becomes His responsibility to hold and keep us: "The Lord is faithful, who shall stablish you, and keep you from evil" (2 Thessalonians 3:3). He says, "If you keep Me enthroned on your heart, I'll keep you blameless until My coming. I'll keep you from falling!" "Commit the keeping of [your] souls to him in well-doing, as unto a faithful Creator" (1 Peter 4:19).